Radiation Synthesis of PVA/ Chitosan Membranes Containing Silver Nanoparticles for Biomedical Applications

Document Type : Original Article


 SILVER NANOPARTICLES (AgNPs) were synthesized by γ-rays of polyvinyl alcohol/ chitosan (PVA/ CS) membranes containing silver nitrate (AgNO3) with promising antimicrobial and biomedical applications. The synthesized silver nanoparticles characterized by Ultra Violet spectroscopy (UV), Fourier transform infrared (FT-IR), X-ray diffraction (XRD), and transmission electron microscopy (TEM). UV studies showed a strong peak around λmax at 420nm. A uniform distribution of silver nanoparticles inside PVA/ CS membranes was achieved by TEM investigation. The prepared silver nanoparticles showed good antimicrobial activity. The membranes containing AgNPs showed non-thrombogenicity effect and slightly haemolytic potential. The prepared membranes containing AgNPs had promising use in biomedical applications.